Answer the following questions: Book Attached.

1.    How does an ADD calculation differ with carcinogenic vs. non-carcinogenic compounds? Please explain the rationale behind this. 1/2 PAGE

2.    Why is calculating a reference dose important? Name at least two UF or MF. 1/2 PAGE

3.    Why is calculating a margin of exposure (MOE) important? What would the MOE of dioxin be and why? Does this pose a concern and why? 1 PAGE