Regulation of glycolysis and gluconeogenesis is a critical concept in biochemistry and often difficult for students to learn. This assignment allows the student to formulate a presentation on the topic and link this to the regulation of aldolase expression in various tissues of the body.

Give a 25-minute lesson teaching with a PowerPoint presentation. Each of the following topics should be covered (review the rubric for context):

-An overview of the glycolysis and gluconeogenesis pathways
-How aldolase is involved in both glycolysis and gluconeogenesis
-The different isoforms of aldolase and their different expression patterns
-An examination of how Aldolase B expression can be regulated by transcription factors HNF-1, HNF-3, C/EPB, and DBP

The lesson presentation should include a title and reference slide and have between 10-15 content slides. At least four references should be cited (only one can be the textbook).

Nelson, D. L., & Cox, M. M. (2017). Lehninger principles of biochemistry (7th ed.). New York, NY: WH Freeman and Co. ISBN-13: 9781464126116